The G. SCHLENSTEDT Lab Home Page 

Link to the new homepage of the lab 
Our research laboratory investigates nucleocytoplasmic transport of macromolecules across the nuclear pore complex. We study the import and export of proteins and RNAs in the yeast Saccharomyces cerevisiae as a model organism. Transport is mediated by specific shuttling receptors which belong to the importin beta superfamily. The import of proteins containing a classical nuclear localization signal (NLS) is the best understood transport pathway. Several export routes and import pathways independent of classical NLSs have been identified recently. We are especially interested in the role of the various transport receptors, the regulatory function of the Ran GTPase, and the RanGTP-interactor Yrb1p (yeast Ran binding protein 1). We apply a combination of molecular biology, genetics, biochemistry and cell biology techniques.   
Address     
Prof. Dr. Gabriel Schlenstedt   
Medizinische Biochemie und Molekularbiologie   
Universität des Saarlandes, Gebäude 61.4    
D-66421 Homburg, Germany    
phone:  (49) 6841-1647912 (office), 1647911 (lab)    
fax:  (49) 6841-1647938  
E-mail:  gabriel.schlenstedt@uks.eu 		   
  
  
 
Lab members  
phone:  (49) 6841-1647910 (office), 1647911 (lab)  
Silke Guthörl (technician)
Dr. Stefanie Caesar  hefelabor@hotmail.com
Karsten Mayr (technician)
Yiming Chang (graduate student)  chang.yiming@uniklinik-saarland.de
Simone Graß (graduate student)  SGrass@gmx.de
Ute Rothenbusch (graduate student)  ute.rothenbusch@gmx.de
Mahnaz Amini (graduate student)  m.amini@mx.uni-saarland.de
Marc Sawatzki (undergraduate student)  MarcSawatzki@gmx.de
Lorenz Latta (undergraduate student)  lorenz.latta@stud-mail.uni-wuerzburg.de

former lab members  
Jens Solsbacher (Frankfurt)   Ellen Maurer (Homburg)
Patrick Maurer (Kaiserslautern)   Sandra Helfen (Wahlen)
Markus Greiner (Homburg)   Silke Thieser (Homburg)
Silvia Hahn (Heidelberg)   Bernd Pohl (Saarbrücken)
Iris Zengerly (Saarbrücken)   Isa Lobert (Saarbrücken)
Andrés Soto (Schweiz)

Diplomarbeit 
Interessierte Studentinnen/Studenten der Biologie / Biochemie / Chemie können ein Thema im Rahmen einer Diplomarbeit bearbeiten. 
Research activities  
  • Publications
  • Projects

    •    SFB 530   Räumlich-zeitliche Interaktionen  zellulärer Signalmoleküle
       Graduiertenkolleg 1326  Calciumsignale und zelluläre Nanodomänen
       Kompetenzzentrum Molekulare Medizin
        The picture shows a functional fusion of the green fluorescent protein (GFP) and yeast importin beta viewed by fluorescence microscopy. The GFP fusion protein is concentrated at the nuclear envelope.

    Internet Search  
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    Dictionaries  
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    Databases  
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    EMBL Bank UniProt/Swiss-Prot Database
    Yeast Genome Database (SGD) Protein Data Bank (PDB)
    Yeast Genome Project (MIPS) Yeast Genome Analysis Center
     
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  • Science Gateway
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    Organizations  
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    Other links  
    Stellenbörsen jobvector, DrArbeit.de, Doktorandenbörse
    other yeast labs, Heidelberg seminars
    deutsches telephonbuch, deutsche postleitzahlen
    wetter, routenplaner (ViaMichelin), bahn fahrplan, flüge
    Conceptual continuity-the Frank Zappa webring, Frank Zappa links

    Universität des Saarlandes, Universität in Homburg, Medizinische Biochemie 

    Last update Dec 1, 2010
    Gabriel Schlenstedt   bcgsch@uniklinik-saarland.de