The G. SCHLENSTEDT Lab Home Page 

Link to the new homepage of the lab 
Our research laboratory investigates nucleocytoplasmic transport of macromolecules across the nuclear pore complex. We study the import and export of proteins and RNAs in the yeast Saccharomyces cerevisiae as a model organism. Transport is mediated by specific shuttling receptors which belong to the importin beta superfamily. The import of proteins containing a classical nuclear localization signal (NLS) is the best understood transport pathway. Several export routes and import pathways independent of classical NLSs have been identified recently. We are especially interested in the role of the various transport receptors, the regulatory function of the Ran GTPase, and the RanGTP-interactor Yrb1p (yeast Ran binding protein 1). We apply a combination of molecular biology, genetics, biochemistry and cell biology techniques.  
 
Address     
Prof. Dr. Gabriel Schlenstedt   
Medizinische Biochemie und Molekularbiologie   
Universität des Saarlandes, Gebäude 61.4    
D-66421 Homburg, Germany    
phone:  (49) 6841-1647912 (office), 1647911 (lab)    
fax:  (49) 6841-1647938  
E-mail:  gabriel.schlenstedt@uks.eu 
  
  
  
 

Lab members  
phone:  (49) 6841-1647910 (office), 1647911 (lab)  
Silke Guthörl (technician)
Dr. Stefanie Caesar  hefelabor@hotmail.com
Karsten Mayr (technician)
Yiming Chang (graduate student)  chang.yiming@uniklinik-saarland.de
Simone Graß (graduate student)  SGrass@gmx.de
Ute Rothenbusch (graduate student)  ute.rothenbusch@gmx.de
Mahnaz Amini (graduate student)  m.amini@mx.uni-saarland.de
Marc Sawatzki (undergraduate student)  MarcSawatzki@gmx.de
Lorenz Latta (undergraduate student)  lorenz.latta@stud-mail.uni-wuerzburg.de

former lab members  
Jens Solsbacher (Frankfurt)   Ellen Maurer (Homburg)
Patrick Maurer (Kaiserslautern)   Sandra Helfen (Wahlen)
Markus Greiner (Homburg)   Silke Thieser (Homburg)
Silvia Hahn (Heidelberg)   Bernd Pohl (Saarbrücken)
Iris Zengerly (Saarbrücken)   Isa Lobert (Saarbrücken)
Andrés Soto (Schweiz)


Diplomarbeit 
Interessierte Studentinnen/Studenten der Biologie / Biochemie / Chemie können ein Thema im Rahmen einer Diplomarbeit bearbeiten. 

Research activities  
  • Publications
  • Projects

  •    SFB 530   Räumlich-zeitliche Interaktionen  zellulärer Signalmoleküle
       Graduiertenkolleg 1326  Calciumsignale und zelluläre Nanodomänen
       Kompetenzzentrum Molekulare Medizin

        The picture shows a functional fusion of the green fluorescent protein (GFP) and yeast importin beta viewed by fluorescence microscopy. The GFP fusion protein is concentrated at the nuclear envelope.



    Internet Search  
      Hotbot, Altavista, Excite, Go, Metacrawler, Webcrawler, Yahoo.com
      Google, Lycos.de, Yahoo.de, web.de, Wikipedia, Wissen.de

    Dictionaries  
      Webster Gateway
      yourdictionary.com
      German - English dictionary LEO
     
    Databases  
    Medline (PubMed NCBI) Genome Database
    Scopus (abstract and indexing database)  Prosite Database
    GenBank (NCBI)  
    EMBL Bank UniProt/Swiss-Prot Database
    Yeast Genome Database (SGD) Protein Data Bank (PDB)
    Yeast Genome Project (MIPS) Yeast Genome Analysis Center
     
    Journals  

  • Science Gateway
  • HighWire Press (Stanford)
  • MolBio journals (Highveld)
  • Journal Seek (Genamics)
  • Analytical Biochemistry Journal of Immunology
    Annual Reviews Journal of Molecular Biology
    Biochemistry Journal of Virology
    Biochimica et Biophysica Acta (BBA) Journal of Structural Biology
    Cell Molecular Biology of the Cell (MBC)
    Cold Spring Harbor Laboratory Press Molecular and Cellular Biology (MCB)
    Current Biology Molecular Cell
    Current Opinions Molecular Genetics and Genomics (MGG)
    EMBO Journal Nature                     Nature - deutsch
    EMBO Reports Nature Cell Biology
    European Journal of Cell Biology Nature Reviews Molecular Cell Biology
    FASEB Journal Nucleic Acid Research
    FEBS Journal (Eur. J. Biochem.) Oncogene
    FEBS Letters PNAS
    Gene Science
    Genes and Development Structure
    Genetics Traffic
    Journal of Biological Chemistry (JBC) Trends (TIBS, TICB, TIG)
    Journal of Cell Biology (JCB) Virology
    Journal of Cell Science Yeast
     
    News  
    Tagesschau Focus Berliner Zeitung
    N24 Der Spiegel Frankfurter Allgemeine
    Yahoo News Stern Frankfurter Rundschau
    Sport Die Zeit  Saarbrücker Zeitung
    Time Magazine   Süddeutsche Zeitung
    New York Times Findling Tagesspiegel
    CNN 2. hand TAZ
     
    Companies  
  • BioSupplyNet
  • BioFind
  • Research & Education Tools  
  • Amos' www links (ExPASy)
  • Cellnucleus.com
  • Antibody Resource Page
  • Molecular biology protocols
  • BCM Search Launcher
  • Pedro's BioMolecular Research Tools
  • Cell & Molecular Biology online
  • S. cerevisiae information (SGD)
  •  
    Organizations  
  • ASCB
  • ESF
  • Cold Spring Harbor Laboratory
  • ASM
  • FASEB
  • Gordon Research Conferences
  • DAAD
  • FEBS
  • Keystone Symposia
  • DFG
  • GBM
  • Max-Delbrück-Center
  • EMBO
  • Pasteur Institute
  • Max-Planck-Gesellschaft
  •  
    Other links  
    Stellenbörsen jobvector, DrArbeit.de, Doktorandenbörse
    other yeast labs, Heidelberg seminars
    deutsches telephonbuch, deutsche postleitzahlen
    wetter, routenplaner (ViaMichelin), bahn fahrplan, flüge
    Conceptual continuity-the Frank Zappa webring, Frank Zappa links

    Universität des Saarlandes, Universität in Homburg, Medizinische Biochemie 


    Last update Dec 1, 2010
    Gabriel Schlenstedt   bcgsch@uniklinik-saarland.de